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Objectives: To conduct a systematic review and meta-analysis regarding the efficacy and safety of inhaled corticosteroids for COPD exacerbations.Exclusion: Previous placebo-controlled trials; previous uncontrolled trials between COPD patients and placebo; and any other potential confounding variables, anabolic steroids list. In case of conflict with other published trials, the final result would have been published, but the researchers decided not to do so in the current review.Data Sources: Medline, Web of Science, MEDLINE (January 1990 to December 2010), EMBASE, National Library of Medicine, ClinicalTrials, qatar desertcart com review.gov, CENTRAL, and the Cochrane Library, qatar desertcart com review.Study Selection: There was no conflict of interest in the research being carried out by both researchers. The authors independently selected the studies for inclusion and excluded any that were unpublished on or after the release date of their initial publications, qatar desertcart review com. Articles were eligible for the reviews if they had enrolled both (or multiple) consecutive patients with chronic obstructive pulmonary disease, had published efficacy results, and had their results published in English, German, or Spanish, anabolic steroids names.Data Extraction and Synthesis: The researchers extracted information such as the intervention arm used, the intervention size, the duration of therapy, the outcomes, and the overall effect size, from study data, anabolic steroids pills buy. The researchers also conducted a sensitivity analysis by removing studies that were unpublished.Results: Six randomised controlled trials (n=2,834) and one controlled clinical trial (n=4,868) participated in the review, anabolic steroids top 10. Of these studies, only two had data on the primary outcome measure for the asthma exacerbation during asthma controlled therapy. All of the trials used inhalable corticosteroids with a dose ranging from 100–2000 mg. All of the included studies reported on the clinical outcomes, including the response to therapy and overall survival, anabolic steroids qatar. In some trials, patients who were initially classified as having a "high response rate" were later changed to a "low response rate" and therefore may have failed to have a significant outcome (for example, the low response rate in the placebo controlled study in the present review and in one of the studies in the Cochrane review). Only one study reported a meta-analysis of published efficacy data, anabolic steroids yellow.Conclusion: Although there were inconsistencies in published safety and efficacy data among included studies, the majority of included trials have shown no evidence of harmful effects of inhaled corticosteroids and may also have shown evidence of beneficial effects.
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