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According to a review of medical literature published in the British Journal of Pharmacology, hGH supplements have a well-documented hypertrophic effect on muscle tissue."It's difficult to see how these drugs would be effective," says Dr. David Goldblatt, an endocrinologist and spokesperson for the US Department of Health and Human Services at the National Institutes of Health, part of the National Institutes of Health.The FDA did not respond to requests for comment.While the FDA does not ban the human use of hGH, which would allow hGH products to be sold with an expiration date, the agency does not recommend prescribing any. However, there is a small but growing body of research suggesting the benefits of hGH use are well-documented.In fact, researchers at the University of Pittsburgh's School of Medicine found that men who have increased their levels of the amino acid leucine by 30 percent had a 33 percent reduction in risk of dying from a heart attack or stroke and a 33 percent reduction in risk of prostate cancer.Yet despite those impressive results, doctors must adhere to strict guidelines. Those guidelines include limiting the doses of hGH to a minimum of 20 milligrams a day — though there are exceptions for rare diseases like cystic fibrosis or HIV. And they are supposed to not administer any drugs in the body when given with a supplement containing hGH."People get very excited about the positive things that are happening with hGH," says Dr. Tom McNeill, a cardiovascular specialist at the Cleveland Clinic.Similar articles: